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Aman Jain
Submitted 2019-03-06 07:16:02 Anticoagulant Reversal Drugs Industry
The global anticoagulant reversal drugs market expected to grow at compound annual growth rate (CAGR) of 15.3% during the forecast period from 2018 to 2026.
Reversing the effects of anticoagulants including novel oral anticoagulants (NOACs), Vitamin K antagonist and others is a major concern in clinical practice especially during life-threatening bleeding episodes and emergency surgery. Approvals of NOACs in last decade has increased the usage of these factor Xa inhibitors in preventing and treating various medical conditions such as stroke T. J. Watt Womens Jersey , pulmonary embolism, atrial fibrillation, and deep vein thrombosis (DVT). However, this growth in anticoagulants usage has led to the rise in the incidence of hospitals admissions and death due to increased bleeding due to anticoagulation. According to Centers for Disease Control and Prevention (CDC) Authentic T. J. Watt Jersey , in the year 2016, approximately 117,000 people were hospitalized in U.S. alone and close to 2,000 deaths per month attributable to anticoagulation or factor Xa inhibitor related bleeding. These factors have led to furious research and development of anticoagulant reversal agents. The U.S. Food and Drug Administration (FDA) and European Medicines Agency (EMA) has granted special status and accelerated approvals for development and swift market entry of certain anticoagulant antidotes.

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The global anticoagulant reversal drugs market is poised to grow during the forecast period owing to approval of blockbuster drugs in the recent years and strong pipeline driving the market. The U.S. Food and Drug Administration has designated Andexxa (the most recent approved drug for factor Xa inhibitors) as orphan drug and tagged under accelerated approval process. European Medicines Agency is also positive to grant approval for andexanet alfa T. J. Watt Jersey , with Committee for Medicinal Products for Human Use (CMPH) reviewing the application. Idarucizumab, approved in 2015 for antidote for dabigatran during atrial fibrillation, is currently under clinical trials for multiple conditions such as hemorrhage and stroke. Thus strong pipeline and governmental initiatives will drive the market for anticoagulant reversal drugs market. Drugs type such as prothrombin complex concentrates, Vitamin K, desmopressin which were earlier preferred for contain emergency situation will demonstrate sluggish growth due to launch of novel drugs with better efficacy and quicker effect. However, high prices of patented drugs would act as a growth barrier in emerging economies